July 12, 2016
Infection with HIV may be associated with accelerated cellular aging, according to a new study in which researchers analyzed DNA methylation patterns of men with HIV infection (Gross AM et al. Mol Cell. 2016;62:157-168). The study provides a possible explanation for why people with HIV who take antiretroviral medications often develop age-related conditions such as cardiovascular disease, hypertension, bone fractures, and renal failure years earlier than those who are uninfected (Guaraldi G et al. Clin Infect Dis. 2011;53:1120-1126).